Abstract
The aim of this study is to assess the accuracy of microalbuminuria (MA) to predict
the mortality in pediatric intensive care unit (PICU). Between December 2014 and November
2015, 250 patients who were 1 month to 18 years old monitored at least 24 hours in
PICU and met study criteria were included. Spot urine samples were measured for microalbuminuria.
Pediatric Risk of Mortality III-24 and Pediatric Multiple Organ Dysfunction scores
were calculated by using the worst parameters in first 24 hours. The collected data
were analyzed with statistical methods and compared with mortality scoring systems
and observed mortality. MA values were significantly higher in nonsurvivors than the
average of the survivors (18 vs. 48 mg/g, p < 0.05). The receiver operating characteristics curve analysis showed that the areas
under the curves for MA was 0.81 at a cut-off value of 32 mg/g, MA measured in 24 hours
of admission to PICU may be able to discriminate between patients a with sensitivity
of 85.2, specificity of 70.8%, positive predictive value of 31.5%, and negative predictive
value of 96.8%. MA is a useful tool to predict mortality in PICU.
Keywords
microalbuminuria - intensive care - mortality - pediatric - childhood